Besides vaccine the company also manufactures antisera, blood plasma, and hormone products. The company's product lines was expanded to include different types of vaccines against bacterial or virus infections, combination vaccines, influenza vaccine, and meningococcal vaccine. Among the first products the Serum Institute of India manufactured in large quantities were the tetanus antitoxin, snake antivenom, DPT vaccine, and MMR vaccine. The company set out to produce immunobiologicals, which were imported into India at high prices. The Serum Institute of India was founded in 1966 in Pune.
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